(Download) "In Vitro Evaluation of Bacopa Monniera on Anti-Helicobacter Pylori Activity and Accumulation of Prostaglandins." by Phytomedicine: International Journal of Phytotherapy & Phytopharmacology ~ eBook PDF Kindle ePub Free

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eBook details

Title: In Vitro Evaluation of Bacopa Monniera on Anti-Helicobacter Pylori Activity and Accumulation of Prostaglandins.
Author : Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
Release Date : January 01, 2003
Genre: Life Sciences,Books,Science & Nature,
Pages : * pages
Size : 207 KB

Description

Summary Bacopa monniera is an Indian tratidional medicine widely used to improve intellectual functions. Earlier, we had reported the prophylactic and curative effects of standardized extract of Bacopa monniera (BME) in various gastric ulcer models. The effect was due to augmentation of the defensive mucosal factors like increase in mucin secretion, life span of mucosal cells and gastric antioxidant effect rather than on the offensive acid-pepsin secretion. The present study includes evaluation of standardized BME (bacoside A content--35.5 [+ or -] 0.9) on other contributing factors towards ulcerogenesis. BME in the dose of 1000 [micro]g/ml showed anti-Helicobacter pylori activity in vitroI and in the dose of 10 [micro]g/ml increased in vitro of prostanoids (PGE and PG[I.sub.2]) in human colonic mucosal incubates. It may be concluded that these factors may contribute to antiulcerogenic activity of BME.